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KMID : 1009020180160020224
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Clinical Psychopharmacology and Neuroscience
2018 Volume.16 No. 2 p.224 ~ p.227
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Donepezil for Compulsive Behavior in Degenerative Dementia: Case Series
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Mishra Biswa Ranjan
Sreeraj Vanteemar S.
Dhanashekaran Saranya
Maiti Rituparna
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Abstract
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Diagnosing and managing dementia, presenting with compulsions is challenging. Presented are three cases, a possible representative subset of the Donepezil responders. Selective degeneration of dorsolateral prefrontal cortex networking striatum leading to compulsions would be amenable to cholinergic modulation.
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KEYWORD
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Repetition compulisons, Psychosis, Dementia, Major neurocognitive disorder, Donepezil
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